Prevalence Rates of E. Coli from Diabetic Foot Infections with their Antibiotic Susceptibility Patterns
Abstract
Introduction Diabetic foot infections (DFIs) are among the most severe complications of diabetes. The aim of this study is to study the prevalence of E. coliand its antibiotic susceptibility pattern involved in diabetic foot infections.
Methods A cross sectional study was done during the period of 6 months (December, 2020 to June, 2021) from AL-Hussein Medical City and AL-Kafeel Hospital at Karbala. Thirty-sixdiabetic foot ulcer patients were included in this study. Swabs were processed for isolation and identification the causative agent of infection and subsequently, antibiotic susceptibility patterns were determined using VITEK 2 compact system.
Results A total of 75of aerobic bacteriawas identified from patients with DFI, of them, 14(19%) Escherichia coli. the highest resistance rate was found to Ampicillin, Amoxicillin, and Tetracycline, followed by 3rd generation cephalosporins and Levofloxacin. Whereas, the highest sensitivity rates were found to Carbapenems and Amikacin.
Conclusions. The prevalence rates of E. coli isolated from DFI were the highest compared to other gram negative bacteria14 (19%). The most effective therapeutic agents toE. coli is Carbapenems and Amikacin.
